Lower-limb-powered prostheses can provide users with volitional control of ambulation. To this end, they require a sensing modality that reliably interprets user intention to move. Ultrasound has been shown to have better resolution and specificity than surface EMG. However, this technology has yet to be integrated into lower-limb prostheses. In this paper, we show that A-mode ultrasound sensing can reliably predict the prosthesis walking kinematics of individuals with a transfemoral amputation. Ultrasound features from the residual limb of 9 transfemoral amputee subjects were recorded with A-mode ultrasound during walking with their passive prosthesis. The manuscript is freely available at this link: A-Mode Ultrasound-Based Prediction of Transfemoral Amputee Prosthesis Walking Kinematics via an Artificial Neural Network | IEEE Journals & Magazine | IEEE Xplore